Kinetic disposition of morphine in young males after intravenous loading and maintenance infusions
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چکیده
منابع مشابه
Cerebral and lung kinetics of morphine in conscious sheep after short intravenous infusions.
BACKGROUND The analgesic effects of morphine are delayed relative to its concentration in blood. The rate of equilibration of morphine between blood and brain may contribute to this delay, but the kinetics of this process have not been modelled. This was determined in conscious instrumented sheep. The lung kinetics of morphine were also determined given their importance in defining systemic kin...
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Teicoplanin is an investigational glycopeptide antibiotic that is structurally and microbiologically similar to vancomycin. Since teicoplanin possesses a very long elimination half-life, the manufacturer suggests that the drug be administered every 12 h for the first day of therapy and once daily thereafter. We studied the multiple-dose (6 mg/kg per dose) pharmacokinetics of teicoplanin in volu...
متن کاملFat embolism in infancy after intravenous fat infusions.
Four cases of fat embolism are described in infants receiving prolonged intravenous infusion of fat (Intralipid 20%). This therapeutic complication has been termed 'fat overloading syndrome' but bears a clinical similarity to post-traumatic fat embolism. These 4 cases are the first to be recorded in infancy, and with histopathological proof of fat embolism. These 4 cases are the first to be rec...
متن کاملMassive Intravenous Infusions *
Some of the factors governing the development of edema in the lungs are understood in broad terms. These factors are considered to be no different from those operative in the systemic vessels-increased hydrostatic pressure, decreased oncotic pressure, excessive permeability of the vessels, and decreased lymphatic drainage. Little specific quantitative information is available relative to the pu...
متن کامل[Comparison of intravenous and epidural morphine analgesia after thoracotomy.].
BACKGROUND AND OBJECTIVES Patients undergoing thoracotomy experience severe postoperative pain. This study aimed at evaluating postoperative analgesia with the association of intravenous and epidural morphine as compared to a single route. METHODS Participated in this study 20 patients of both genders, physical status ASA I, II or III, scheduled for thoracotomy. Patients were premedicated wit...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1986
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03010823